Centers for Disease Control and Preventionpublic health agencyCDC historydisease preventionAtlanta Georgia headquarters

CDC Agency Overview: History, Organization, and Public Health Mission

Understanding the Centers for Disease Control and Prevention (CDC) The Centers for Disease Control and Prevention (CDC) serves as the United States' premier national public health agency....

Understanding the Centers for Disease Control and Prevention (CDC)

The Centers for Disease Control and Prevention (CDC) serves as the United States' premier national public health agency. Operating under the United States Department of Health and Human Services, the CDC is tasked with protecting public health and safety through the control and prevention of disease, injury, and disability. From managing global health threats to monitoring domestic health trends, the agency plays a critical role in the stability of the nation's healthcare landscape.

The Communicable Disease Center moved to its current headquarters in 1960. Building 1 is pictured in 1963.
The Communicable Disease Center moved to its current headquarters in 1960. Building 1 is pictured in 1963.
: The Communicable Disease Center moved to its current headquarters in 1960. Building 1 is pictured in 1963.

Key Facts

Arlen Specter Headquarters and Emergency Operations Center
Arlen Specter Headquarters and Emergency Operations Center
  • Established: July 1, 1946
  • Headquarters: Atlanta, Georgia, U.S.
  • Parent Agency: U.S. Department of Health and Human Services
  • FY24 Annual Budget: US$11.581 billion
  • Workforce: Approximately 11,815 employees
  • Primary Mission: Protecting public health through disease prevention and control

Agency History and Evolution

CDC Building 17 in Atlanta, Georgia, as seen from Emory University
CDC Building 17 in Atlanta, Georgia, as seen from Emory University

The CDC has undergone several name changes and structural evolutions since its inception. Its roots trace back to the Office of National Defense Malaria Control Activities (1942) and the Office of Malaria Control in War Areas (1942–1946). On July 1, 1946, it was officially formed as the Communicable Disease Center.

Over the decades, the agency's identity shifted to reflect its expanding scope:

  • Communicable Disease Center (1946–1967)
  • National Communicable Disease Center (1967–1970)
  • Center for Disease Control (1970–1980)
  • Centers for Disease Control (1980–1992)

CDC's Roybal campus in Atlanta, Georgia
CDC's Roybal campus in Atlanta, Georgia
: CDC's Roybal campus in Atlanta, Georgia

Leadership and Recent Transitions

The agency has been led by numerous directors since its early years. Recent leadership has seen significant transitions. Following the tenure of Mandy Cohen, the agency entered a period of acting leadership. As of February 2026, Jay Bhattacharya serves as the Acting Director.

The agency has also faced internal challenges, including a leadership dispute and the resignation of several senior officials, such as Debra Houry (Chief Medical Officer), Demetre Daskalakis (Director of the National Center for Immunization and Respiratory Diseases), and Daniel Jernigan (Director of the National Center for Emerging and Zoonotic Infectious Diseases).

Organizational Structure and Focus Areas

Donald Henderson as part of the CDC's smallpox eradication team in 1966
Donald Henderson as part of the CDC's smallpox eradication team in 1966

The CDC is a massive organization divided into various Centers, Institutes, and Offices (CIOs). These specialized units allow the agency to address specific health concerns with scientific precision.

Core National Centers

The agency's work is distributed across several key centers, including:

  • National Center for Immunization and Respiratory Diseases: Focuses on vaccine-preventable illnesses.
  • National Center for Emerging and Zoonotic Infectious Diseases: Monitors diseases that jump from animals to humans.
  • National Institute for Occupational Safety and Health (NIOSH): Focuses on worker safety and preventing work-related injuries.
  • National Center for Chronic Disease Prevention and Health Promotion: Addresses long-term health issues like heart disease and diabetes.
  • Global Health Center: Manages international health security and cooperation.

David Sencer points to a depiction of Triatomine sp., which transmits Chagas disease.
David Sencer points to a depiction of Triatomine sp., which transmits Chagas disease.
: David Sencer points to a depiction of Triatomine sp., which transmits Chagas disease.

Major Areas of Scientific Focus

The CDC's scientific mandate covers a broad spectrum of public health disciplines:

  • Communicable Diseases: Managing infectious outbreaks like influenza and HIV/AIDS.
  • Non-communicable Diseases: Addressing chronic conditions and lifestyle-related health risks.
  • Vaccine Safety: Monitoring the safety and efficacy of immunizations.
  • Environmental Health: Studying the impact of toxins and environmental factors on human health.
  • Traveler's Health: Providing guidance and health levels (Watch, Alert, and Warning) for international travel.

CDC and MSF staff preparing to enter an Ebola treatment unit in Liberia, August 2014
CDC and MSF staff preparing to enter an Ebola treatment unit in Liberia, August 2014
: CDC and MSF staff preparing to enter an Ebola treatment unit in Liberia, August 2014

Data, Publications, and Resources

A cornerstone of the CDC's authority is its ability to collect and disseminate high-quality health data. The agency utilizes various systems to track health trends across the United States.

Key Data Systems and Publications

The CDC provides essential tools for researchers and the public, including:

  • CDC WONDER: A wide-ranging online database for epidemiologic research.
  • Morbidity and Mortality Weekly Report (MMWR): The agency's primary vehicle for scientific publication and weekly health updates.
  • Emerging Infectious Diseases: A monthly journal focusing on new infectious threats.

Tom Harkin Global Communications Center
Tom Harkin Global Communications Center
: Tom Harkin Global Communications Center

Summary of Agency Profile

CDC Agency Overview
Category Details
Headquarters Location Atlanta, Georgia, USA
Primary Jurisdiction Federal Government of the United States
Key Departments ATSDR, NIOSH
Major Publications MMWR, Emerging Infectious Diseases
Budget (FY24) $11.581 Billion

Frequently Asked Questions

What is the main purpose of the CDC?

The CDC's primary mission is to protect public health by preventing and controlling diseases, injuries, and other health threats through scientific research, data surveillance, and public health guidance.

Where is the CDC located?

The agency is headquartered in Atlanta, Georgia, where it operates three major campuses in the metropolitan area.

What are the CDC travel health levels?

The CDC uses a three-level system for travelers: Level 1 (Watch) suggests practicing usual precautions; Level 2 (Alert) suggests enhanced precautions; and Level 3 (Warning) advises avoiding nonessential travel.

What is the role of NIOSH within the CDC?

The National Institute for Occupational Safety and Health (NIOSH) is a department within the CDC that focuses on preventing work-related injuries and illnesses and regulates safety equipment like N95 respirators.

How does the CDC track disease outbreaks?

The agency uses various data systems, such as CDC WONDER, and specialized centers like the Center for Forecasting and Outbreak Analytics to monitor, track, and respond to emerging health threats.

References

  1. "Centers for Disease Control and Prevention Salary Statistics". federalpay.org. Retrieved November 20, 2025.
  2. "Centers for Disease Control and Prevention". United States Department of Health and Human Services. October 4, 2019. Archived from the original on April 10, 2020. Retrieved May 15, 2020.
  3. Niesse, Mark. "City of Atlanta's expansion to Emory and CDC approved". Atlanta Journal-Constitution. Retrieved December 5, 2017.
  4. "Mission, Role and Pledge". Centers for Disease Control and Prevention. April 14, 2014. Archived from the original on January 18, 2017.
  5. "Home: CDC". cdc.gov. Retrieved November 19, 2008.